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2020年05月31日
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Angus Imrie, Anya Taylor-Joy;
Directed by=Autumn de Wilde;
Year=2020;
Eleanor Catton;
Emma. is a movie starring Anya Taylor-Joy, Johnny Flynn, and Mia Goth. In 1800s England, a well meaning but selfish young woman meddles in the love lives of her friends;
7,7 / 10

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Omg the alarm “by the seaside” has traumatised me for life. Literally I heard it here and I had a heart attack, late nights of revision killed me.

EMMA LYSM YOU ARE AMAZING😍💓💕🤩😘💖💗❤💘💜🧡💛.
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Sounds like a preachy feminist rant instead of the wonderful story of an independent minded young woman. Alcott knew what she was writing when she wrote it.
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Lmafo I love how they just add miranda at the end Such News. Here Me think she saying such Fun


Me after my 7th mental breakdown that week. also i feel so bad she seems so upset 😢.

I actually enjoy her content, without the worry of wasting my time and energy. Weird right? Like if this isnt YouTube where you come to waste time watching any and everything ANYWAY. oh wait IT IS.
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I loved Winona as Jo, that movie was a big part of my childhood. But i think Saoirse is perfect for Jo.


Emma: talks about how she has no friends, is unsophisticated, and life is boring me: actually has no friends, is VERY unsophisticated and life is boring asf * OH.
You can use * to search for partial matches.
Logical Operator Operator
Open Access Article
1
HBM Partners, 6300 Zug, Switzerland
2
Institute for Medical Informatics, Statistics and Epidemiology (IMISE), University Leipzig, 04107 Leipzig, Germany
3
European Center for Pharmaceutical Medicine, University of Basel, 4056 Basel, Switzerland
4
Interdisciplinary Breast Center, Kantonsspital Baden, 5404 Baden, Switzerland
*
Author to whom correspondence should be addressed.
Received: 30 January 2020 / Accepted: 7 February 2020 / Published: 13 February 2020
Breast cancer is the most common cancer in women worldwide and the solid tumor type for which the highest number of drugs have been approved to date. This study examines new drug approvals for breast cancer by the United States Food and Drug Administration (FDA) and the European Medicines Agency (EMA), based on an analysis of regulatory documents from both agencies for the period from 1995 to 2018. Of the 29 breast cancer drugs approved over this time span, 17 received positive decisions from both the FDA and EMA, including all drugs licensed after 2008. Nineteen of the 25 FDA-approved drugs, but none of the EMA approvals, benefited from special regulatory pathways (such as fast track, breakthrough therapy, or priority review). In the U. S. A., four accelerated approvals were granted (of which one, for bevacizumab, was later revoked), while only two drugs received provisional approvals following EMA review. New breast cancer drugs were approved approximately twelve months earlier in the United States than in Europe. These results suggest that a broader use of special regulatory pathways by EMA could help to accelerate access to novel drugs for European breast cancer patients.
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
MDPI and ACS Style
Leo, C. P. ; Hentschel, B. ; Szucs, T. D. ; Leo, C. FDA and EMA Approvals of New Breast Cancer Drugs—A Comparative Regulatory Analysis. Cancers 2020, 12, 437.
Show more citation formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.
Article Access Map by Country/Region.


Yall are so dramatic, yes this vid is nonsense, but youre like “her videos are not the same anymore” “I dont find her funny anymore” and tomorrow she posts sth cool and yall change your mind. Chill out idiots lmao.


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She reminds me of Margaery Tyrell (Natalie Dormer) 🤔.


 


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最終更新日  2020年05月31日 22時40分24秒
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